Glutamate , 1 aminocyclopentane trans 1 , 3 dicarboxylic acid ( an agonist of metabotropic glutamate receptors ) , and alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid ( an agonist of ionotropic glutamate receptors ) stimulated also tyrosine phosphorylation of pp 110 and pp 120 . ^^^ |