| Interacting proteins: O43524 and O15111 |
Pubmed |
SVM Score :0.0 |
| Lysates of cells were subjected to Western blot analyses of IKK alpha , IKK beta , p 65 ( RelA ) subunit of nuclear factor kappaB ( NF kappaB ) , total Akt , phospho Akt ( Ser 473 ) , and phospho FKHR ( Thr 24 ) / phosphor FKHRL 1 ( Thr 32 ) . ^^^ |
|
| Interacting proteins: O43524 and O15111 |
Pubmed |
SVM Score :0.0 |
| IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a . ^^^ We provide evidence for such a mechanism by showing that IkappaB kinase ( IKK ) physically interacts with , phosphorylates , and inhibits FOXO3a independent of Akt and causes proteolysis of FOXO3a via the Ub dependent proteasome pathway . ^^^ |
|
| Interacting proteins: O43524 and O15111 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43524 and O15111 |
Pubmed |
SVM Score :0.0 |
| NA |
|