| Interacting proteins: O14965 and P38398 |
Pubmed |
SVM Score :0.0 |
| Aurora A regulates centrosome function during M phase through its interactions with various cell cycle regulators including TACC , chTOG , Ajuba , BRCA 1 , LATS 2 , and p 53 . ^^^ |
|
| Interacting proteins: O14965 and P38398 |
Pubmed |
SVM Score :0.0 |
| Various biological parameters have been studied clinically for their ability to predict response to docetaxel , such as parameters related to : ( 1 ) efflux ( p glycoprotein ) and metabolism ( CYP3A4 ) ; ( 2 ) beta tubulin ( somatic mutation of beta tubulin and changes in beta tubulin isotypes levels ) ; ( 3 ) cell cycle ( HER 2 , BRCA 1 and Aurora A ) ; and ( 4 ) apoptosis ( p 53 , BCL 2 and thioredoxin ) . ^^^ |
|
| Interacting proteins: O14965 and P38398 |
Pubmed |
SVM Score :0.0 |
| In addition , a growing number of other proteins have been implicated in centrosomal regulation of the DNA damage response , e . g . the tumor suppressor p 53 , the breast cancer susceptibility gene product BRCA 1 and mitotic regulators such as Aurora A , Nek 2 and the Polo like kinases Plk 1 and Plk 3 . ^^^ |
|
| Interacting proteins: O14965 and P38398 |
Pubmed |
SVM Score :0.0 |
| NA |
|