Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
It is expressed after two hrs in T 84 cells treated with TPA , reaching a maximum response by four hrs . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
Blood lymphocytes from 26 women were cultivated in RPMI 1640 for 72 hrs with or without dexamethasone , dbcAMP , and TPA . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
The applied HRS measurement procedure also enables simultaneous detection of two photon absorption ( TPA ) fluorescence . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
The presence of IL 2 in the supernatants of splenocytes from GM 1 / P ( 1mg / Kg , i . v . , , day 1 ) treated mice stimulated with Con A or Con A plus TPA for 48 hrs was evaluated by proliferation of an IL 2 dependent CTLL cell line . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
HRs disappeared after prolonged or repeated application of 5 HT , indicating an apparent desensitization . 4 . 5 HT induced HRs were completely inhibited by the protein kinase C ( PKC ) activator phorbol 12 myristate 13 acetate ( TPA ) ( 100 nM ) . ^^^ TPA ( 100 nM ) blocked the GTP gamma S plus 5 HT potentiated HRs after the first four to five HRs . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
Only TPA exerted a significant clastogenic activity at non cytotoxic concentrations ( 10 ( 8 ) to 10 ( 6 ) M ) measured after 24 and 48 hrs . ^^^ Chromosomal aberrations including gaps and breaks were predominantly of the chromatid type ; they are first measurable after 6 8 hrs , i . e . as soon as the cells recover from TPA induced G 2 inhibition . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
GTP [ S ] induced HRs were inhibited by the PKC agonists phorbol 12 myristate 13 acetate ( TPA ) ( 100 nM ) and 1 , 2 dioctanoyl glycerol ( diC 8 ) ( 250 microM ) . ^^^ TPA or sphingosine did not alter InsP 3 induced HRs . ^^^ Adding TPA ( 100 nM ) before insemination caused a reduction in the frequency of HRs at fertilization , but neither TPA nor sphingosine affected the frequency or size of HRs when they were added after the start of fertilization . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
After 24 hrs of 5 microM 12 0 tetradecanoyl phorbol 13 acetate ( TPA ) treatment , PKC directed histone phosphorylation and acute TPA effects on glucose transport were lost , but PKC dependent vinculin phosphorylation was still evident . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
The present work reports that non toxic concentrations of the tumor promoter TPA , stimulate the adherence of murine peritoneal macrophages after short time incubation , while TPA pretreatment for periods longer than 4 hrs suppresses phagocytosis , RNA and protein synthesis by these cells . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
In kinetic pulse experiments TPA enhanced 3H thymidine incorporation in density inhibited cells stimulated by fresh serum but only after markedly suppressing incorporation 8 13 hrs after serum stimulation . ^^^ When cells arrested by serum deprivation were pretreated with TPA , fresh serum stimulation led to initiation of 3H TdR incorporation 5 hrs earlier than untreated controls . ^^^ However , TPA addition at the time of serum stimulation did not lead to a suppression at 8 13 hrs , whereas enhancement was observed during peak incorporation times regardless of whether the cells were pretreated with TPA during serum deprivation . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
None of these agents except TPA and A 23187 had any effect on ACTH secretion from the cell line in short ( 0 8 hrs ) or long term ( 1 4 days ) cultures . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
Growth arrest of HL 60 cells , caused by 10 nM phorbol ester 12 O tetradecanoylphorbol 13 acetate ( TPA ) induced monocytic / macrophage like differentiation for 72 hrs . , has been accompanied by a 50 % decrease in UBF1 / 2 mRNAs expression . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
When cells were pre incubated with proteasome inhibitor MG 132 for 3 hrs , followed by TPA for another 12 hrs , TPA induced RXRalpha degradation was inhibited . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
We show that hrs of AcMNPV additionally carry , in the interpalindromic sequences , a large number of cAMP response elements ( CRE ) and TPA response elements ( TRE ) , known to bind ubiquitous cellular transcription factors of the bZIP family . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
Although t PA alone ( 2 mg / kg over 2 hrs ) lowered thrombus weight significantly , there was no evidence of flow restoration . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
To determine the role of tissue type plasminogen activator ( t PA ) and immediate percutaneous transluminal coronary angioplasty ( PTCA ) in treating patients with evolving transmural myocardial infarction , 50 patients received t PA ( 1 . 25 mg / kg 4 over 3 hrs ) or placebo according to 3 : 1 double blind randomization 3 . 8 + / 1 . 1 hr after onset of symptoms . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
Fifty percent lysis in 5 hrs was obtained with about 5 IU / ml of endogenous t PA or with 10 IU / ml of exogenous t PA . ^^^ The presence of both exogenous ( 10 IU / ml ) and endogenous ( 5 IU / ml ) t PA resulted in 50 percent lysis in 1 . 5 hrs , indicating that t PA incorporated in a thrombus contributes significantly to its lysis by exogenous t PA . ^^^ Spontaneous clot lysis within 5 hrs was only observed with post occlusion clots in pre or post occlusion plasma in two subjects in whom the t PA level rose to 10 15 IU t PA / ml . ^^^ In the five other subjects with post occlusion t PA levels below 2 IU / ml , no clot lysis was observed within 24 hrs . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
When the HPASMCs ( passage 4 or 5 ) were conditioned with NG R 1 , a dose ( 0 . 01 100 micrograms NG R1 / ml for 24 hrs . ) dependent increase in t PA an u PA synthesis was observed , which was significant from 1 microgram NG R1 / ml on . t PA antigen increased from 2 . 4 + / 0 . 1 to 4 . 7 + / 0 . 5 ng / 10 ( 5 ) cells / 24 hrs . ; u PA antigen increased from 1 . 8 + / 0 . 1 to 3 . 0 + / 0 . 4 ng / 10 ( 5 ) cells / 24 hrs . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
Under the same experimental conditions , quercetin significantly increased t PA ( n = 6 , P < 0 . 01 , at 4 h EC 50 = 0 . 71 microM and at 24 hrs EC 50 = 0 . 74 microM ) . ^^^ |
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Interacting proteins: P40939 and O14964 |
Pubmed |
SVM Score :0.0 |
INTERVENTIONS : t PA was administered with a median dose of 0 . 3 mg . kg ( 1 ) . hr ( 1 ) ( range , 0 . 008 1 . 13 ) and a median duration of 9 hrs ( range , 1 . 2 83 ) . ^^^ |
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