| Interacting proteins: P08581 and O14964 |
Pubmed |
SVM Score :0.0 |
| Furthermore , AP 1 cooperates with NF kappa B and stimulates expression of the cell cycle regulator cyclin D 2 , proto oncogene c met and the lymphocyte homing receptor CCR 7 , which are all strongly expressed in primary HRS cells . ^^^ |
|
| Interacting proteins: P08581 and O14964 |
Pubmed |
SVM Score :0.0 |
| Both tumor susceptibility gene 101 ( TSG 101 ) / human VPS ( hVPS ) 28 and hepatocyte growth factor receptor substrate ( Hrs ) cytosolic complexes bind ubiquitin agarose . ^^^ |
|
| Interacting proteins: P08581 and O14964 |
Pubmed |
SVM Score :0.0 |
| In contrast , depletion of hepatocyte growth factor receptor substrate ( Hrs ) only modestly inhibits EGF degradation , does not induce tubulation of the early endosome , and causes the generation of enlarged MVBs that retain the ability to fuse with the lysosome . ^^^ |
|
| Interacting proteins: P08581 and O14964 |
Pubmed |
SVM Score :0.0 |
| In contrast to hemoglobins , ligand binding to the deoxy and met forms is noncooperative for brachiopod ( and sipunculid ) Hrs . ^^^ |
|
| Interacting proteins: P08581 and O14964 |
Pubmed |
SVM Score :0.0 |
| Adrenal medulla and other tissues were analyzed for met and leu enkephalins by RIAs and norepinephrine and epinephrine by HPLC EC at 4 hrs , 3 , 10 , 16 and 30 days post SAH . ^^^ Concurrently , at 4 hrs and 3 days post SAH , the adrenal medulla was depleted 47 % of met and 53 % of leu enkephalins . ^^^ |
|
| Interacting proteins: P08581 and O14964 |
Pubmed |
SVM Score :0.0 |
| Reduction of cellular Hrs levels by short interfering RNA modestly retards Met degradation and markedly prevents the attenuation of Met phosphorylation . ^^^ HGF dependent Hrs phosphorylation and Met dephosphorylation may provide signatures for retention of the receptor in coated regions of the endosome implicated in sorting to lysosomes . . ^^^ |
|
| Interacting proteins: P08581 and O14964 |
Pubmed |
SVM Score :0.0 |
| Total energy ( MET hrs ) and peak strain scores were calculated . ^^^ |
|
| Interacting proteins: P08581 and O14964 |
Pubmed |
SVM Score :0.0 |
| We propose that this reflects polyubiquitin dependent sorting of Met , as the overexpression of ubiquitin but not K48R ubiquitin also restores hepatocyte growth factor dependent phosphorylation of the endosomal coat protein Hrs from inhibition by lactacystin . ^^^ |
|
| Interacting proteins: P08581 and O14964 |
Pubmed |
SVM Score :0.0 |
| Met / Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation . ^^^ Although Met Y1003F undergoes endosomal trafficking and localizes with the cargo sorting protein Hrs , it is unable to induce phosphorylation of Hrs . ^^^ |
|
| Interacting proteins: P08581 and O14964 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08581 and O14964 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08581 and O14964 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08581 and O14964 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08581 and O14964 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08581 and O14964 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08581 and O14964 |
Pubmed |
SVM Score :0.0 |
| NA |
|