| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| PCT in the CABG group rose to a maximum of 2 . 0 ng / ml ( median ) at 15 hrs postoperatively . ^^^ |
|
| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| DESIGN : Prospective study , assessing the course of PCT serum levels in early ( within 72 hrs after onset ) ARDS . ^^^ INTERVENTIONS : Serum samples were drawn every 4 6 hrs for measurement of PCT , neopterin , IL 6 , and CRP concentrations . ^^^ PCT serum levels were significantly higher ( p < . 0005 ) in the patients with septic ARDS than in patients with nonseptic ARDS within 72 hrs after onset of ARDS . ^^^ |
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| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| In a human liver slice model , the release of PCT , SAA , and CRP was measured on induction with rhTNF alpha and rhIL 6 for 24 hrs . ^^^ After rhTNF alpha administration , PCT reached half maximal concentrations within 8 hrs , 12 hrs earlier than either SAA or CRP did . ^^^ |
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| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| MEASUREMENTS AND MAIN RESULTS : PCT was significantly elevated over baseline after ILP with a maximum between 8 hrs ( peak level 16 . 0+ / 18 . 8 ( SD ) ng / mL ) and 36 hrs ( 13 . 8+ / 15 . 7 ng / mL ) ( p < . 001 ) . ^^^ |
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| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| Sequential PCT levels were available at 0 hrs and 24 hrs in 39 patients ( 52 % ) . ^^^ Of 39 children , 16 ( 41 % ) with sequential PCT measurements showed no fall in PCT after 24 hrs treatment . ^^^ A fall in PCT after 24 hrs of treatment may have favorable prognostic significance . . ^^^ |
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| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| MEASUREMENTS AND MAIN RESULTS : Plasma PCT at baseline was barely detectable , but levels increased significantly ( p < . 05 ) to 2+ / 1 . 8 pg / mL 2 hrs after the start of reperfusion in the shock group , and to 987+ / 230 pg / mL at 4 hrs after E . coli in the sepsis group . ^^^ Interleukin 6 levels paralleled the course of PCT measurements , whereas a significant increase in neopterin was seen at 24 hrs . ^^^ PCT levels were significantly different at 24 hrs between survivors ( 2360+ / 620 pg / mL ) and nonsurvivors ( 4776+ / 563 pg / mL ) in the sepsis group ( p = . 032 ) , as were interleukin 6 ( 1562+ / 267 vs . 4903+ / 608 pg / mL ; p = . 01 ) and neopterin / creatinine ratio ( 0 . 400+ / 0 . 038 vs . 0 . 508+ / 0 . 037 ; p = . 032 ) . ^^^ |
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| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| INTERVENTIONS : Confluent rat vascular smooth muscle cells ( VSMC ) were incubated for 24 hrs and 48 hrs with PCT ( 1 ng / mL , 10 ng / mL , 100 ng / mL , 1 , 000 ng / mL , 5 , 000 ng / mL ) alone or with the combination of tumor necrosis factor alpha ( TNF alpha , 500 U / mL ) plus interferon gamma ( IFN gamma , 100 U / mL ) . iNOS gene expression was measured by qualitative as well as quantitative polymerase chain reaction analysis , NO release was estimated by the modified Griess method . ^^^ MEASUREMENTS AND MAIN RESULTS : PCT in increasing concentrations had no effect on iNOS gene expression and nitrite / nitrate release for 24 hrs and 48 hrs , respectively . ^^^ However , PCT ameliorated TNF alpha / IFN gamma induced iNOS gene expression in a dose dependent manner ( maximal inhibition at PCT 100 ng / mL by 66 % for 24 hrs and 80 % for 48 hrs ) . ^^^ This was accompanied by a significantly reduced release of nitrite / nitrate into the cell culture supernatant ( maximal reduction at PCT 100 ng / mL by 56 % and 45 % for 24 hrs and 48 hrs , respectively ) . ^^^ |
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| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| MEASUREMENTS AND MAIN RESULTS : In a first step , plasma PCT and C reactive protein concentrations were measured preoperatively and until 72 hrs postoperatively in ten consecutive patients who underwent uncomplicated cardiac surgery . ^^^ PCT concentrations increased progressively from the end of cardiopulmonary bypass ( 0 . 09 + / 0 . 09 ng / mL ) , peaked at 24 hrs postoperatively ( 1 . 14 + / 1 . 24 ng / mL ) , and began to decrease at 48 hrs . ^^^ |
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| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| In all 53 patients , PCT and CRP were elevated ( > 0 . 5 ng / mL and > 10 mg / L , respectively ) within 24 hrs after diagnosis . ^^^ Within 48 hrs , however , PCT levels decreased more frequently from baseline in survivors than in nonsurvivors ( 80 % vs . 41 % , p < . 05 ) . ^^^ |
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| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| The FCT ( mean+SD ) , TRC and PCT for the artemether treated group were 32 ( +13 ) hrs , 21 ( +11 ) hrs and 36 ( +18 ) hrs , respectively , while for the quinine treated group the respective figures were 36 ( +18 ) , 26 ( +15 ) hrs and 41 ( +12 ) hrs . ^^^ |
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| Interacting proteins: P06132 and O14964 |
Pubmed |
SVM Score :0.0 |
| The CRT , FCT and PCT were significantly less in the artesunate group ( 50 . 4 + / 31 . 49 hrs ; 43 . 55 + / 20 . 12 hrs , and 41 . 67 + / 16 . 78 hrs respectively ) as compared to the quinine group ( 70 . 15 + / 17 . 56 hrs , 62 . 23 + / 16 . 99 hrs , and 52 . 24 + / 12 . 69 hrs respectively ) ( p < 0 . 05 ) No side effects were observed in the artesunate treated group . ^^^ |
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