| Interacting proteins: Q9UM54 and O14908 |
Pubmed |
SVM Score :0.80330918 |
| We identified a novel interaction between myosin 6 and the GLUT 1 transporter binding protein GLUT1CBP ( GIPC 1 ) and first proposed that as an adapter molecule it might function to couple vesicle bound proteins to myosin 6 movement . 0.80330918^^^ |
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| Interacting proteins: Q9UM54 and O14908 |
Pubmed |
SVM Score :0.0 |
| GLUT1CBP is able to bind to native GLUT 1 extracted from cell membranes , self associate , or interact with the cytoskeletal proteins myosin 6 , alpha actinin 1 , and the kinesin superfamily protein KIF 1B . ^^^ |
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| Interacting proteins: Q9UM54 and O14908 |
Pubmed |
SVM Score :0.0 |
| Three distinct adapter proteins GIPC , Dab 2 and SAP 97 that associate with the cargo binding tail domain of myosin 6 have been identified . ^^^ |
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| Interacting proteins: Q9UM54 and O14908 |
Pubmed |
SVM Score :0.0 |
| GIPC , a PDZ domain containing adapter protein , co assembles with myosin 6 on these vesicles . ^^^ Instead , our data suggest that myosin 6 recruitment to clathrin coated pits may be an early step in the recruitment of GIPC to the vesicle surface . . ^^^ |
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| Interacting proteins: Q9UM54 and O14908 |
Pubmed |
SVM Score :0.0 |
| GIPC , a putative myo 6 tail binding protein , was also present . ^^^ |
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| Interacting proteins: Q9UM54 and O14908 |
Pubmed |
SVM Score :0.0 |
| Here we report that Myo 6 and a Myo 6 binding protein , GIPC 1 , form a complex that can engage TrkB . ^^^ Myo 6 and GIPC 1 were necessary for BDNF TrkB mediated facilitation of long term potentiation in postnatal day 12 13 ( P 12 13 ) hippocampus . ^^^ Moreover , BDNF mediated enhancement of glutamate release from presynaptic terminals depended not only upon TrkB but also upon Myo 6 and GIPC 1 . ^^^ Similar defects in basal synaptic transmission as well as presynaptic properties were observed in Myo 6 and GIPC 1 mutant mice . ^^^ |
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