| Here we report that Myo 6 and a Myo 6 binding protein , GIPC 1 , form a complex that can engage TrkB . ^^^ Myo 6 and GIPC 1 were necessary for BDNF TrkB mediated facilitation of long term potentiation in postnatal day 12 13 ( P 12 13 ) hippocampus . ^^^ Moreover , BDNF mediated enhancement of glutamate release from presynaptic terminals depended not only upon TrkB but also upon Myo 6 and GIPC 1 . ^^^ |