| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| The involvement of the death adaptor proteins FADD / MORT1 , TRADD , and RIP and the apoptosis initiating caspases 8 and 10 in death signaling by the two death inducing TRAIL receptors 1 and 2 ( TRAIL R 1 and TRAIL R 2 ) are controversial . ^^^ |
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| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| Rather , CARDINAL potently suppressed NF kappaB activation associated with overexpression of TRAIL R 1 , TRAIL R 2 , RIP , RICK , Bcl 10 , and TRADD , or through ligand induced stimulation of the interleukin 1 or tumor necrosis factor receptors . ^^^ |
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| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| Sensitization of PSC with culture duration was accompanied by increased expression of CD 95 and TRAIL receptor 2 and no alterations of Flip expression or protein kinase B phosphorylation but was paralleled by the appearance of a COOH terminal cleavage product of receptor interacting protein . ^^^ |
|
| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| Thus , both DR 5 and DR 4 use FADD , TRADD , and RIP in their signal transduction pathways , and FADD is the common mediator of apoptosis by all known death domain containing receptors . . ^^^ |
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| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| TRADD and RIP , which bound TNFR 1 , did not bind DR 4 and DR 5 . ^^^ |
|
| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| Our results showed that the expression levels of DR 5 , the activation levels of caspase 8 , 3 and RIP were critical factors in determining TRAIL sensitivities in Jurkat cells . ^^^ |
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| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| During TRAIL DR 4 , DR 5 signaling , this pathway is activated by interactions of activated Fas associated death domain with activated receptor interacting protein ( RIP ) , which in turn activates NF kappaB inducing kinase and phosphorylates IkappaB . ^^^ |
|
| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| Whereas exposure to 3 Cl AHPC results in NF kappaB activation , it inhibits the expression of XIAP , c IAP 1 , and Bcl 10 ( L ) and enhances the expression of proapoptotic molecules , including the death receptors DR 4 and DR 5 as well as Fas and Rip 1 . ^^^ |
|
| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| In other experiments , we found no evidence for dominant RIP suppression by the Spore killer haplotypes Sk 2 and Sk 3 . . ^^^ |
|
| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O14763 and Q13546 |
Pubmed |
SVM Score :0.0 |
| NA |
|