| Interacting proteins: O14653 and O75396 |
Pubmed |
SVM Score :0.0 |
| Membrin , Sec22b , and Ykt 6 were not found in the 112 kDa complex . ^^^ |
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| Interacting proteins: O14653 and O75396 |
Pubmed |
SVM Score :0.0 |
| The proposed cis Golgi vesicle receptor syntaxin 5 was found in a complex with Golgi associated SNARE of 28 kDa ( GOS 28 ) , rbet 1 , rsly 1 , and two novel proteins characterized herein : rat sec22b and membrin , both cytoplasmically oriented integral membrane proteins . ^^^ The complex appears to recapitulate vesicle docking interactions of proteins originating from distinct compartments , since syntaxin 5 , rbet 1 , and GOS 28 localize to Golgi membranes , whereas mouse sec22b and membrin accumulate in the endoplasmic reticulum . ^^^ |
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| Interacting proteins: O14653 and O75396 |
Pubmed |
SVM Score :0.0 |
| Purified recombinant syntaxin 5 , membrin , and rbet 1 , three Q SNAREs , assemble cooperatively to create a high affinity binding site for sec22b , an R SNARE . ^^^ Interestingly , although sec22b binds to the combination of syntaxin 5 , membrin , and rbet 1 , it can only bind if it is present while the others assemble ; sec22b can not bind to a pre assembled ternary complex of syntaxin 5 , membrin , and rbet 1 . ^^^ |
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| Interacting proteins: O14653 and O75396 |
Pubmed |
SVM Score :0.0 |
| This contrasts with a second distinct SNARE complex , also required for intra Golgi transport , consisting of syntaxin 5 ( Sed 5 ) membrin ( Bos 1 ) ERS 24 ( Sec 22 ) rBet 1 ( Bet 1 ) , whose 5 ( rBet 1 ) and t SNARE subunits ( membrin and ERS 24 ) , progressively decrease in concentration toward the trans face . ^^^ |
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| Interacting proteins: O14653 and O75396 |
Pubmed |
SVM Score :0.0 |
| Here we demonstrate that hsc 70 chaperones stimulate in vitro SNARE complex formation among the ER / Golgi SNAREs syntaxin 5 , membrin , rbetl and sec22b , under conditions in which assembly is normally inhibited . ^^^ |
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