Interacting proteins: Q8TAA9 and O14640 |
Pubmed |
SVM Score :0.0 |
Vangl 1 ( Strabismus 2 ) and Vangl 2 ( Strabismus 1 or Ltap ) are mammalian homologs of Drosophila Vang interacting with PRICKLE 1 , PRICKLE 2 , ANKRD 6 , DVL 1 , DVL 2 , DVL 3 , KAI 1 and MAGI 3 . ^^^ |
|
Interacting proteins: Q8TAA9 and O14640 |
Pubmed |
SVM Score :0.0 |
Using a yeast two hybrid system , glutathione S transferase pull down and co immunoprecipitation assays , we show that both mouse Vangl 1 and Vangl 2 physically interact with the three members of the cytoplasmic Dishevelled ( Dvl ) protein family . ^^^ |
|
Interacting proteins: Q8TAA9 and O14640 |
Pubmed |
SVM Score :0.0 |
Human VANGL 1 , VANGL 2 ( Van Gogh homologs ) , CELSR 1 , CELSR 2 , CELSR 3 ( Starry night homologs ) , DVL 1 , DVL 2 , DVL 3 ( Dishevelled homologs ) , PRICKLE 1 , PRICKLE 2 ( Prickle homologs ) , and ANKRD 6 ( Diego homolog ) are core PCP signaling molecules . ^^^ |
|
Interacting proteins: Q8TAA9 and O14640 |
Pubmed |
SVM Score :0.0 |
Reasoning that Celsr 3 and Fzd 3 might interact with PCP orthologues in mammals like they do in flies , we used mRNA in situ hybridization to compare the expression of Celsr 3 and Fzd 3 with that of dishevelled 1 , 2 and 3 ( Dvl 1 3 ) , van gogh like 1 and 2 ( Vangl 1 , 2 ) , and prickle like 1 and 2 ( Prickle 1 , 2 ) , during mouse CNS development , from embryonic day 10 . 5 to postnatal day 21 . ^^^ |
|
Interacting proteins: Q8TAA9 and O14640 |
Pubmed |
SVM Score :0.0 |
WNT5A , WNT5B , WNT 11 , FZD 3 , FZD 6 , VANGL 1 , VANGL 2 , DVL 1 , DVL 2 , DVL 3 , PRICKLE 1 , PRICKLE 2 , ANKRD 6 , NKD 1 , NKD 2 , DAAM 1 , DAAM 2 , CELSR 1 , CELSR 2 , CELSR 3 , ROR 1 and ROR 2 are planar cell polarity ( PCP ) signaling molecules implicated in the regulation of cellular polarity , convergent extension , and invasion . ^^^ |
|
Interacting proteins: Q8TAA9 and O14640 |
Pubmed |
SVM Score :0.0 |
NA |
|