| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Dishevelled ( Dsh / Dvl ) proteins are known to mediate Wnt signaling by up regulating beta catenin levels and stimulating T cell factor ( TCF ) / LEF 1 dependent transcription . ^^^ By contrast , all three conserved domains of Dvl , including DIX , PDZ , and DEP , are required for up regulation of beta catenin and for stimulation of LEF 1 mediated transcription in mammalian cells . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Furthermore , Wnt 3a containing conditioned medium down regulated Axin and accumulated beta catenin in L cells and expression of Dvl 1 ( DeltaPDZ ) , in which the PDZ domain was deleted , suppressed this action of Wnt 3a . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta catenin stability . ^^^ Dvl 1 inhibited Axin promoted glycogen synthase kinase 3beta dependent phosphorylation of beta catenin , and the DIX domain of Dvl 1 was required for this inhibitory activity . ^^^ Expression of Dvl 1 in L cells induced the nuclear accumulation of beta catenin , and deletion of the DIX domain abolished this activity . ^^^ These results indicate that the DIX domains of Dvl 1 and Axin are important for protein protein interactions and that they are necessary for the ability of Dvl 1 and Axin to regulate the stability of beta catenin . . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| We found that treatment with a soluble Wnt 3A leads to hyperphosphorylation of Dvl proteins and a concomitant elevation of the cytoplasmic beta catenin levels in mouse NIH3T3 , L , and C57MG cells . ^^^ Furthermore , we showed that mouse Dvl proteins affect downstream components of Drosophila Wg signaling as Dsh does ; overexpression of Dvl proteins in clone 8 cells results in elevation of Armadillo ( Drosophila homolog of beta catenin ) and Drosophila E cadherin levels , hyperphosphorylation of Dvl proteins themselves , and inhibition of Zeste White 3 kinase mediated phosphorylation of a microtubule binding protein , Tau . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Axin forms a complex with adenomatous polyposis coli gene product , glycogen synthase kinase 3beta ( GSK 3beta ) , beta catenin , Dvl , and protein phosphatase 2A and functions as a scaffold protein in the Wnt signaling pathway . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Moreover , the expression of dishevelled 1 , an upstream regulatory molecule of the cellular beta catenin content , was observed in vascular endothelial cells in the infarct area . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Idax inhibited Wnt and Dvl but not beta catenin induced axis duplication . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Axin , a negative regulator of the Wnt signaling pathway , forms a complex with glycogen synthase kinase 3beta ( GSK 3beta ) , beta catenin , adenomatous polyposis coli ( APC ) gene product , and Dvl , and it regulates GSK 3beta dependent phosphorylation in the complex and the stability of beta catenin . ^^^ The binding site of PR61beta on Axin was different from those of GSK 3beta , beta catenin , APC , and Dvl . ^^^ Although PR61beta did not affect the stability of beta catenin , it inhibited Dvl and beta catenin dependent T cell factor activation in mammalian cells . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Wnt proteins transduce their signals through dishevelled ( Dvl ) proteins to inhibit glycogen synthase kinase 3beta ( GSK ) , leading to the accumulation of cytosolic beta catenin and activation of TCF / LEF 1 transcription factors . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Thus , in balloon cells , elevated cytoplasmic levels of dishevelled ( Dvl 1 ) protein were accompanied by an absence of Notch 1 , increased adenomatous poliposis coli ( APC ) , altered cytoplasmic beta catenin , and reduced nuclear expression of beta catenin . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Other components of the Wnt signalling pathway , including Dvl , glycogen synthase kinase 3beta , beta catenin , and adenomatous polyposis coli , interact with Axin , and the phosphorylation and stability of beta catenin are regulated in the Axin complex . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| PP2C exists in a complex with Dvl , beta catenin , and Axin , a negative regulator of Wnt signaling . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Other components of the Wnt signaling pathway , including Dvl , glycogen synthase kinase 3beta ( GSK 3beta ) , beta catenin , and adenomatous polyposis coli ( APC ) , interact with Axin , and the phosphorylation and stability of beta catenin are regulated in the Axin complex . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| CK 2 and beta catenin co precipitate with the Dvl proteins , which are Wnt signaling intermediates . ^^^ A major phosphoprotein of the size of beta catenin appears in in vitro kinase reactions performed on the Dvl immunoprecipitates . ^^^ In vitro translated beta catenin , Dvl 2 , and Dvl 3 are phosphorylated by CK 2 . ^^^ The selective CK 2 inhibitor apigenin blocks proliferation of Wnt 1 transfected cells , abrogates phosphorylation of beta catenin , and reduces beta catenin and Dvl protein levels . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Here we show that both CKI delta and CKI epsilon interacted directly with Dvl 1 , and that CKI phosphorylated multiple components of the Wnt regulated beta catenin degradation complex in vitro , including Dvl 1 , adenomatous polyposis coli ( APC ) , axin , and beta catenin . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Rfz 9 overexpression induces the hyperphosphorylation and relocalization of mouse Dishevelled 1 ( Dvl 1 ) from the cytoplasm to the cell membrane and the accumulation of cytosolic beta catenin . ^^^ Deletion mutant analysis determines that there is a difference in Rfz 9 C terminal residues required for the modifications of Dvl 1 and those required for the inductions of beta catenin stabilization and TCF transactivation . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Dishevelled ( Dvl or Dsh ) signals downstream of Wnt receptors and stabilizes beta catenin during cell proliferation and embryonic axis formation . ^^^ Mutation of the actin binding motif abolishes the cytoskeletal localization of Dvl , but enhances Wnt / beta catenin signalling and axis induction in Xenopus . ^^^ By contrast , mutation of the phospholipid interaction site disrupts vesicular association of Dvl , Dvl phosphorylation , and Wnt / beta catenin pathway activation . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Either low expression of Dvl or CKIepsilon alone did not accumulate beta catenin , but their co expression accumulated greatly . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| When the cells were transfected with the SMT3IP2 / Axam2 C500A mutant , which had neither isopeptidase nor carboxyl terminal hydrolase activity , or with the 1 352 mutant , which lacked the catalytic domain of the enzyme , again the beta catenin disappeared , indicating that the enzyme activities were not necessary for the instability of beta catenin in this transfection assay system and that its competition with Dvl for binding to Axin may be important for the instability of beta catenin as suggested previously for Axam ( Kadoya , T . , Kishida , S . , Fukui , A . , Hinoi , T . , Michiue , T . , Asashima , M . , and Kikuchi , A . ( 2000 ) J . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| We found that PS 1 destabilizes the cytoplasmic and nuclear pools of beta catenin when stabilized by Wnt or Dvl but not when stabilized at lower levels of the Wnt pathway . ^^^ PS 1 also inhibited the transcriptional activity of endogenous beta catenin , and the PS 1 mutants were again less inhibitory at the level of Dvl but showed a different pattern of inhibition toward transcription below Dvl . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Dvl proteins participate as key intermediates in signal transmission from the seven membrane spanning Frizzled receptors leading to inhibition of glycogen synthase kinase 3beta ( GSK 3beta ) , stabilization of beta catenin , and activation of the lymphoid enhancer factor ( LEF ) transcription factor . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Dishevelled 1 ( DVL 1 ) is thought to act as a positive regulator of the wnt signalling pathway , and inhibits GSK3beta activity preventing beta catenin degradation and thus allowing wnt target gene expression . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| In the canonical pathway , Wnt receptors activate Dishevelled ( Dvl ) , which then blocks the degradation of a key signal transducer , beta catenin , leading to the nuclear accumulation of beta catenin and induction of Wnt target genes through TCF / LEF family transcription factors . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Casein kinase 1 epsilon enhances the binding of Dvl 1 to Frat 1 and is essential for Wnt 3a induced accumulation of beta catenin . ^^^ Coexpression of Dvl 1 and Frat 1 caused accumulation of beta catenin synergistically in L cells . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Dishevelled ( DVL ) proteins are WNT signaling molecules implicated in beta catenin pathway and PCP pathway . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Through several cytoplasmic relay components including DVL 1 , the human counterpart of the Drosophila disheveled gene , the signal is transduced to beta catenin , which then enters the nucleus and forms a complex with T cell factor ( TCF ) to activate transcription of Wnt target genes . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Wnt signaling activates the gene encoding DVL 1 ; the latter suppresses beta catenin by promoting its degradation through enhanced inactivation of glycogen synthase kinase 3 ( GSK 3 ) . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Western blot analysis was conducted to confirm the expression of Dishevelled ( Dvl ) and cytosolic beta catenin in matched autologous tissue samples ( tumor and normal pleura ) , malignant pleural effusions , and in established mesothelioma cell lines LRK1A , REN and H 513 . ^^^ Thirteen of 15 mesotheliomas examined showed consistent overexpression of Dvl and increased cytosolic beta catenin levels as compared with controls . ^^^ In mesothelioma cells tested , DeltaPDZ Dvl mediated inhibition of Dvl decreased cytosolic beta catenin levels , diminished Tcf mediated transcription , and suppressed tumorigenesis of LRK1A and REN in vitro and in vivo . ^^^ Our data suggest that in malignant pleural mesothelioma , Wnt signaling is activated through Dvl overexpression and downstream signaling through beta catenin . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| To assess potential roles of the Wnt family in human endometrium , an endocrine responsive tissue , we investigated in the proliferative and secretory phases of the menstrual cycle , endometrial expression of several Wnt ligands ( Wnt 2 , Wnt 3 , Wnt 4 , Wnt 5a , Wnt 7a , and Wnt 8b ) , receptors [ Frizzled ( Fz ) 6 and low density lipoprotein receptor related protein ( LRP ) 6 ] , inhibitors [ FrpHE and Dickkopf ( Dkk ) 1 ] , and downstream effectors ( Dishevelled 1 , glycogen synthase kinase 3beta , and beta catenin ) by RT PCR , real time PCR and in situ hybridization . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Furthermore , the nuclear translocation and formation of vesicular structures of beta catenin were induced by BP 75 and Dvl 1 in a synergistic manner . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| To evaluate the biological significance of Wnt signaling and , in particular , Dvl function in lung cancer , we transfected siRNA ( designed to inhibit selectively human Dvl 1 , 2 , and 3 ) , to the NSCLC cell line H 1703 , which is known to have beta catenin mediated Tcf dependent transcriptional activity . ^^^ Here , we demonstrate that Dvl specific siRNA treatment in H 1703 decreases significantly Dvl and beta catenin expression , resulting in reduction of Tcf dependent transcriptional activity , and , importantly , growth inhibition . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Inhibition of GSK 3beta by DVL increases beta catenin stability and TCF transcriptional activation . ^^^ In turn , DVL stabilizes microtubules by inhibiting GSK 3beta through a transcription and beta catenin independent pathway . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| BACKGROUND : Dvl is a cytoplasmic protein to regulate the stability of beta catenin in the Wnt signalling pathway . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Dishevelled ( Dvl ) protein plays a central role in this pathway by transducing the signal from the Wnt receptor complex to the beta catenin destruction complex . ^^^ We show that deleting the C terminal two thirds of Dvl , which includes the PDZ and DEP domains and is essential for Dvl induced JNK activation , rendered the molecule a much more potent activator of the beta catenin pathway . ^^^ We also observed a correlation between the localization and the signaling activity of Dvl in the beta catenin pathway and the JNK pathway . ^^^ Furthermore , by using RNA interference , we demonstrate that the Drosophila CKIepsilon homologue Double time positively regulates the beta catenin pathway through Dvl and negatively regulates the Dvl induced JNK pathway . ^^^ We suggest that CKIepsilon functions as a molecular switch to direct Dvl from the JNK pathway to the beta catenin pathway , possibly by altering the conformation of the C terminus of Dvl . . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Overexpression of Dvl 1 abrogated H2O2 induced downregulation of beta catenin . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Moreover , XSENP 1 inhibits ectopic axis induction by Dvl , beta catenin and the constitutively active form of beta catenin , but not by siamois . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Associated Wnt signaling components , including low density lipoprotein receptor related protein 5 ( LRP 5 ) , kremen 1 , dickkopf 1 ( Dkk 1 ) , secreted Frizzled related peptide ( sFRP ) 2 , sFRP 3 , sFRP 4 , Disheveled ( Dvl ) , GSK 3beta , adenomatous polyposis coli ( APC ) , beta catenin , T cell factor ( TCF ) 1 , and TCF 4 , were also identified . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| This model takes into account several observations reported here : the identification of intracellular residues of Frizzled required for beta catenin signaling and for recruitment of Dvl to the plasma membrane ; evidence that Wnt3A binds to the ectodomains of LRP and Frizzled ; and demonstrations that a requirement for Wnt ligand can be abrogated by chimeric receptors that allow formation of Frizzled LRP hetero oligomers . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Taken together , these results suggest that Dvl induces cytoskeletal and morphologic rearrangements in neuronal differentiating N2A cells through a mechanism that can not be attributed exclusively to modulation of GSK3beta or beta catenin activity , but which does depend upon a DIX domain / vesicle association dependent signaling pathway . . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Dishevelled ( Dvl ) , a key activator of the pathway , inhibits the adenomatous polyposis coli complex , and this leads to the accumulation of beta catenin and promotes tumorigenesis . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Wnt ligands bind their receptors Frizzled and low density lipoprotein receptor related protein 5 / 6 and function through Disheveled ( Dvl ) , Axin , adenomatous polyposis coli , glycogen synthase kinase 3beta , and casein kinase ( CK ) 1 to stabilize beta catenin and induce lymphocyte enhancer binding factor ( LEF ) / T cell factor ( TCF ) dependent transcriptional activities . ^^^ From this screen , both known components and previously uncharacterized regulators of this pathway were identified , including beta catenin , Dvl 1 , Dvl 3 , Fbxw 1 , Cul 1 , CK1epsilon , CK1delta , and gamma catenin . ^^^ In particular , a previously unrecognized activator , LRRFIP 2 ( leucine rich repeat in Flightless interaction protein 2 ) , was found that interacts with Dvl to increase the cellular levels of beta catenin and activate beta catenin / LEF / TCF dependent transcriptional activity . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Dishevelled ( Dvl ) is a positive regulator of the canonical Wnt signaling pathway , which regulates the levels of beta catenin . ^^^ The beta catenin oncoprotein depends upon the association of Dvl and Axin proteins through their DIX domains , and its accumulation directs the expression of specific developmental related genes at the nucleus . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| In the canonical pathway , two DIX domain containing proteins , Dishevelled ( Dvl ) and Axin , regulate the degradation of beta catenin that activates Wnt target genes through TCF / LEF family transcription factors . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| By analyzing cellular proteins that regulate beta catenin stabilities , it was found that RONDelta 160 activates the protein disheveled ( DVL ) and inactivates glycogen synthase kinase 3beta by Ser 9 residue phosphorylation . ^^^ Thus , the oncogenic RON variant regulates beta catenin stabilities through activation of DVL and inactivation of glycogen synthase kinase 3beta . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| The observed abnormalities included overexpression of Wnt 1 , Frizzled 1 and 2 receptors , Dishevelled 1 , downregulation of Secreted frizzled related protein 1 , GSK 3beta inactivation , microsatellite instability at the Axin locus as well as induction of beta catenin target genes , such as glutamine synthetase , glutamate transporter 1 , and Wisp 1 . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| In the `` canonical ' ' Wnt signaling pathway , Disheveled ( Dvl ) is required to functionally inhibit the activity of the GSK3beta / Axin complex and thereby stabilize beta catenin . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Regulation of dishevelled and beta catenin in rat skeletal muscle : an alternative exercise induced GSK 3beta signaling pathway . beta catenin is a multifunctional protein involved in cell cell adhesion and the Wnt signaling pathway . beta Catenin is activated upon its dephosphorylation , an event triggered by Dishevelled ( Dvl ) mediated phosphorylation and deactivation of glycogen synthase kinase 3beta ( GSK 3beta ) . ^^^ Immunoblotting demonstrated that Dvl , Axin , GSK 3beta , and beta catenin proteins are expressed in rat red and white gastrocnemius muscles . ^^^ Treadmill running exercise in vivo significantly decreased beta catenin phosphorylation in both muscle types , with complete dephosphorylation being elicited by maximal exercise . beta Catenin dephosphorylation was intensity dependent , as dephosphorylation was highly correlated with muscle glycogen depletion during exercise ( r ( 2 ) = 0 . 84 , P < 0 . 001 ) . beta Catenin dephosphorylation was accompanied by increases in GSK 3beta Ser ( 9 ) phosphorylation and Dvl GSK 3beta association . ^^^ In contrast to exercise , maximal insulin treatment ( 1 U / kg body wt ) had no effect on skeletal muscle beta catenin phosphorylation or Dvl GSK 3beta interaction . ^^^ In conclusion , exercise in vivo , but not insulin , increases the association between Dvl and GSK 3beta in skeletal muscle , an event paralleled by beta catenin dephosphorylation . . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Wnt3a treatment transiently disrupted the Dvl 1 / Smad1 interaction coincident with nuclear accumulation of beta catenin . ^^^ In contrast , when cells were exposed to both Wnt3a and BMP 2 , there was an enhanced accumulation of the Dvl 1 Smad 1 complex and a decreased nuclear accumulation of beta catenin . ^^^ These results identify a potential mechanism whereby BMP 2 antagonizes Wnt signaling in osteoblast progenitors by promoting an interaction between Smad 1 and Dvl 1 that restricts beta catenin activation . . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Recently , the DVL 1 gene was identified as a middle molecule of the Wnt / beta catenin signaling pathway . ^^^ The abnormality of beta catenin in prostate cancer has been well studied , so the examination of the DVL 1 gene in prostate cancer is appealing . ^^^ In addition , DVL 1 and beta catenin protein expression was evaluated with a new validated set of 20 prostate cancers . ^^^ In addition , a correlation between DVL 1 expression and beta catenin expression was confirmed . ^^^ CONCLUSIONS : DVL 1 was overexpressed in prostate cancer and its overexpression might be related to prostate cancer progression through the Wnt / beta catenin pathway . . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| In addition , spatial expression analysis of Dishevelled ( Dvl ) and beta catenin in the fracture callus revealed an identical pattern of expression with both proteins localizing in osteoprogenitor cells of the periosteum , osteoblasts and proliferating / pre hypertrophic chondrocytes . ^^^ Further , in vitro knockdown of all three Dvl isoforms in chondrocytes using small interfering RNAs ( siRNA ) leads to partial inhibition of cell proliferation and differentiation , decreased expression of chondrogenic markers ( ColII , ColX , Sox 9 ) and suppressed nuclear accumulation of unphosphorylated beta catenin . ^^^ |
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| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| Dishevelled ( Dvl ) transduces signals from the Wnt receptor , Frizzled , to downstream components , leading to the stabilization of beta catenin and subsequent activation of the transcription factor T cell factor ( TCF ) and / or lymphoid enchancer factor ( LEF ) . ^^^ These data suggest a relationship between the Wnt beta catenin pathway and redox signalling through redox sensitive association of NRX with Dvl . . ^^^ |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and O14640 |
Pubmed |
SVM Score :0.0 |
| NA |
|