Interacting proteins: O14579 and P53621 |
Pubmed |
SVM Score :0.0 |
In a screen for high copy suppressors of these defects , we isolated the previously unidentified yeast epsilon COP gene . epsilon COP ( Sec28p ) overproduction suppresses the defects of ret 1 3 cells up to 34 degrees C , through stabilizing levels of alpha COP . ^^^ Our results suggest that a function of epsilon COP is to stabilize alpha COP and the coatomer complex . . ^^^ |
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Interacting proteins: O14579 and P53621 |
Pubmed |
SVM Score :0.0 |
The yeast Saccharomyces cerevisiae gene encoding the epsilon COP subunit is known as SEC28 / ANU2 . anu 2 null mutant cells ( anu2Delta ) are temperature sensitive , and alpha COP is rapidly degraded in these cells when they are shifted to the restrictive temperature . ^^^ These results are discussed in terms of evidence that epsilon COP plays a critical role in maintaining the structural integrity of alpha COP . . ^^^ |
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Interacting proteins: O14579 and P53621 |
Pubmed |
SVM Score :0.0 |
The last approximately 170 amino acids of alpha COP are also non essential for cell viability , but required for epsilon COP incorporation into coatomer and maintainance of normal epsilon COP levels . ^^^ |
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Interacting proteins: O14579 and P53621 |
Pubmed |
SVM Score :0.0 |
Strong interaction with alpha COP requires the presence of comparable amounts of epsilon COP or beta ' COP . ^^^ |
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Interacting proteins: O14579 and P53621 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: O14579 and P53621 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: O14579 and P53621 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: O14579 and P53621 |
Pubmed |
SVM Score :0.0 |
NA |
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