| Interacting proteins: O00471 and Q96A65 |
Pubmed |
SVM Score :0.0 |
| In addition to Sec6p , Sec8p and Sec15p , the complex contains the proteins encoded by SEC 3 , SEC 5 , SEC 10 and a novel gene , EXO 70 . ^^^ |
|
| Interacting proteins: O00471 and Q96A65 |
Pubmed |
SVM Score :0.0 |
| The exocyst consists of eight components : Sec 3 , Sec 5 , Sec 6 , Sec 8 , Sec 10 , Sec 15 , Exo 70 , and Exo 84 . ^^^ |
|
| Interacting proteins: O00471 and Q96A65 |
Pubmed |
SVM Score :0.0 |
| Overexpression of truncated , dominant negative SEC 8 or SEC 10 mutants decreased the number of vesicles at the plasma membrane , whereas expression of truncated SEC 6 or SEC 8 inhibited overall insulin secretion . ^^^ When single exocytotic events were imaged by total internal reflection fluorescence microscopy , the fluorescence of the insulin surrogate , neuropeptide Y monomeric red fluorescent protein brightened , diffused , and then vanished with kinetics that were unaffected by overexpression of truncated SEC 8 or SEC 10 . ^^^ |
|
| Interacting proteins: O00471 and Q96A65 |
Pubmed |
SVM Score :0.0 |
| Using biochemical methods , we show that Sec8p physically interacts with other members of the exocyst complex , including Sec6p , Sec10p , and Exo70p . ^^^ |
|
| Interacting proteins: O00471 and Q96A65 |
Pubmed |
SVM Score :0.0 |
| One subset ( Sec5p , Sec6p , Sec8p , Sec10p , Sec15p , and Exo84p ) exhibits mobility similar to that of the vesicle bound Rab family protein Sec4p , whereas Sec3p and Exo70p exhibit substantially more stability . ^^^ |
|
| Interacting proteins: O00471 and Q96A65 |
Pubmed |
SVM Score :0.0 |
| NA |
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