| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| We have observed previously the co immunoprecipitation of the p 85 subunit of phosphatidylinositol 3 kinase ( PI3K ) and SHP 2 in murine lymphohemopoietic cells after stimulation with interleukin 3 . ^^^ We have investigated this interaction in more detail and now report the identification of a potentially novel 100 kDa protein ( termed p 100 ) , which is inducibly phosphorylated on tyrosine after interleukin 3 treatment and which co immunoprecipitates with both p 85 PI3K and SHP 2 . ^^^ Although largely cytosolic , p 100 can be detected associated with SHP 2 and PI3K in crude membrane fractions after interleukin 3 stimulation . ^^^ |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| The related cytokines interleukin 3 ( IL 3 ) , IL 5 , and granulocyte macrophage colony stimulating factor ( GM CSF ) , all induced PI3K activity detected in antiphosphotyrosine immunoprecipitates . ^^^ |
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| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| Interleukin 3 ( IL 3 ) , on the other hand , requires PI3K for survival , and blocking PI3K partially inhibited Bad phosphorylation . ^^^ |
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| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| Two Ras effector pathways leading to the activation of Raf 1 and phosphatidylinositol 3 kinase ( PI3K ) have been implicated in the survival signaling by the interleukin 3 ( IL 3 ) receptor . ^^^ |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08700 and O00329 |
Pubmed |
SVM Score :0.0 |
| NA |
|