Interacting proteins: O00291 and O95782 |
Pubmed |
SVM Score :0.0 |
In the present study we have identified three HIP 1 associated proteins , clathrin heavy chain and alpha adaptin A and C . ^^^ In vitro binding studies revealed that the central coiled coil domain is required for the interaction of HIP 1 with clathrin , whereas DPF like motifs located upstream to this domain are important for the binding of HIP 1 to the C terminal ' appendage ' domain of alpha adaptin A and C . ^^^ |
|
Interacting proteins: O00291 and O95782 |
Pubmed |
SVM Score :0.0 |
HIP 1 contains a clathrin box and AP 2 consensus binding sites that display high affinity binding to the terminal domain of the clathrin heavy chain and the ear domain of the AP 2 alpha subunit , respectively . ^^^ |
|