| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.60689511 |
| We demonstrate Hip1R binding preference for light chains associated with clathrin heavy chain and show that Hip1R stimulation of clathrin assembly in vitro is blocked by mutations in the conserved sequence of light chains that abolish interaction with Hip 1 and Hip1R . 0.60689511^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| Eighteen hips received 10 Gy , 8 hips 20 Gy and , 1 hip 12 Gy . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| Trend analysis showed a significant ( P < 0 . 001 ) change in average position at the hip and knee , extensor angular impulse at the hip , and positive work done at the hip 3 wk after surgery followed by a partial rehabilitation at 5 wk after surgery . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| MATERIAL AND METHOD : A 58 years old female had an irreducible internal rotation of the right hip 3 years after total hip arthroplasty for arthritis . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| CASE DESCRIPTION : The patient was a 68 year old woman who had a comminuted intertrochanteric fracture of the left hip 3 months previously . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| We present a very unusual clinical case of giant cell arteritis with uterus involvement , in a women of 66 years old , that began clinical features of pain and functional limitation of shoulders and hip 3 mouth before been operated of uterus prolapse with hysterectomy . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| Here we report the isolation of a cDNA clone for HIP1R ( huntingtin interacting protein 1 related ) , which encodes a predicted protein product sharing a striking homology with HIP 1 . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| Huntingtin interacting protein 1 related ( Hip1R ) is a novel component of clathrin coated pits and vesicles and is a mammalian homologue of Sla2p , an actin binding protein important for both actin organization and endocytosis in yeast . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| Huntingtin interacting protein 1 ( HIP 1 ) and HIP 12 are orthologues of Sla2p , a yeast protein with essential functions in endocytosis and regulation of the actin cytoskeleton . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| In mice and humans , there are two known members of the Huntingtin interacting protein 1 ( HIP 1 ) family , HIP 1 and HIP 1 related ( HIP1r ) . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| In this report , we have determined the affinity of the I / LWEQ module proteins Talin 1 , Talin 2 , huntingtin interacting protein 1 ( Hip 1 ) , and the Hip 1 related protein ( Hip1R / Hip12 ) for F actin and identified a conserved structural element that interferes with the actin binding capacity of these proteins . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| Huntingtin interacting protein 1 related ( HIP1R ) has a crucial protein trafficking role , mediating associations between actin and clathrin coated structures at the plasma membrane and trans Golgi network . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| HIP 12 is a non proapoptotic member of a gene family including HIP 1 , an interacting protein with huntingtin . ^^^ Additionally , we have identified a novel protein termed HIP 12 with significant sequence and biochemical similarities to HIP 1 and high sequence similarity to Sla2p . ^^^ HIP 12 differs from HIP 1 in its pattern of expression both at the mRNA and protein level . ^^^ However , HIP 1 and HIP 12 are both found within the brain and show a similar subcellular distribution pattern . ^^^ In contrast to HIP 1 , which is toxic in cell culture , HIP 12 does not confer toxicity in the same assay systems . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| The HIP 1 proteins , including HIP 1 and HIP 1 related ( HIP1r ) , have an N terminal polyphosphoinositide interacting epsin N terminal homology , domain , which is found in proteins involved in clathrin mediated endocytosis . ^^^ HIP 1 and HIP1r also share a central leucine zipper and an actin binding TALIN homology domain . ^^^ Here we show that HIP 1 , like HIP1r , colocalizes with clathrin coat components . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| Both Scd5p and yeast clathrin physically associate with Sla2p , a homologue of the mammalian huntingtin interacting protein HIP 1 and the related HIP1R . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| Localization of HIP1R in the small vesicular structures in the spine , possible sites of vesicular transport of synaptic proteins , together with the structure based analysis , suggested a role of HIP1R for vesicle trafficking through interaction with F actin and working together with huntingtin and HIP 1 at the synaptic sites . . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| HIP 1 and HIP1r stabilize receptor tyrosine kinases and bind 3 phosphoinositides via epsin N terminal homology domains . ^^^ Huntingtin interacting protein 1 related ( HIP1r ) is the only known mammalian relative of huntingtin interacting protein 1 ( HIP 1 ) , a protein that transforms fibroblasts via undefined mechanisms . ^^^ Here we demonstrate that both HIP1r and HIP 1 bind inositol lipids via their epsin N terminal homology ( ENTH ) domains . ^^^ Furthermore , the HIP1r ENTH domain , like that of HIP 1 , is necessary for lipid binding , and expression of an ENTH domain deletion mutant , HIP1r / deltaE , induces apoptosis . ^^^ Consistent with the ability of HIP1r and HIP 1 to affect cell survival , full length HIP 1 and HIP1r stabilize pools of growth factor receptors by prolonging their half life following ligand induced endocytosis . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| The novel fission yeast protein Pal1p interacts with Hip 1 related Sla2p / End4p and is involved in cellular morphogenesis . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| Hip 3 interacts with the HIRA proteins Hip 1 and Slm 9 and is required for transcriptional silencing and accurate chromosome segregation . ^^^ Importantly , the function of Hip 1 , Slm 9 , and Hip 3 is not restricted to constitutive heterochromatic loci , since these proteins also repress the expression of a number of genes , including the Tf 2 retrotransposons . . ^^^ |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00291 and O75146 |
Pubmed |
SVM Score :0.0 |
| NA |
|