Interacting proteins: O00253 and P33032 |
Pubmed |
SVM Score :0.0 |
In both conventional and photoemulsion binding studies [ 125I ] AGRP ( 87 132 ) was observed only to bind to cells expressing melanocortin receptors MC3R , MC4R , and MC5R . ^^^ |
|
Interacting proteins: O00253 and P33032 |
Pubmed |
SVM Score :0.0 |
As AgRP is only a weak antagonist of the MC 2 and MC 5 receptors , which are expressed principally by adipocytes and in the adrenal cortex , the question arizes as to the function of peripheral AgRP . ^^^ |
|
Interacting proteins: O00253 and P33032 |
Pubmed |
SVM Score :0.0 |
The study shows that some parts of the MC system are highly conserved through vertebrate evolution , such as regions in POMC coding for ACTH , alpha MSH , and beta MSH , the C terminal region of AGRP , key binding units within the MC1R , MC2R , MC4R , and MC5R , synteny blocks around the MCRs , pharmacological properties of the MC2R , whereas other parts in the system are either missing , such as the MC3R and gamma MSH , or different as compared to mammals , such as the affinity of ACTH and MSH peptides to MC1R and MC4R and the anatomical expression pattern of the MCRs . . ^^^ |
|
Interacting proteins: O00253 and P33032 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: O00253 and P33032 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: O00253 and P33032 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: O00253 and P33032 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: O00253 and P33032 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: O00253 and P33032 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P33032 and O00253 |
Pubmed |
SVM Score :0.0 |
As AgRP is only a weak antagonist of the MC 2 and MC 5 receptors , which are expressed principally by adipocytes and in the adrenal cortex , the question arizes as to the function of peripheral AgRP . ^^^ |
|
Interacting proteins: P33032 and O00253 |
Pubmed |
SVM Score :0.0 |
In both conventional and photoemulsion binding studies [ 125I ] AGRP ( 87 132 ) was observed only to bind to cells expressing melanocortin receptors MC3R , MC4R , and MC5R . ^^^ |
|
Interacting proteins: P33032 and O00253 |
Pubmed |
SVM Score :0.0 |
The study shows that some parts of the MC system are highly conserved through vertebrate evolution , such as regions in POMC coding for ACTH , alpha MSH , and beta MSH , the C terminal region of AGRP , key binding units within the MC1R , MC2R , MC4R , and MC5R , synteny blocks around the MCRs , pharmacological properties of the MC2R , whereas other parts in the system are either missing , such as the MC3R and gamma MSH , or different as compared to mammals , such as the affinity of ACTH and MSH peptides to MC1R and MC4R and the anatomical expression pattern of the MCRs . . ^^^ |
|
Interacting proteins: P33032 and O00253 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P33032 and O00253 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P33032 and O00253 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P33032 and O00253 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P33032 and O00253 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P33032 and O00253 |
Pubmed |
SVM Score :0.0 |
NA |
|